About CAPO

Dr. Ramirez

Dr. Julio A Ramirez

The Community-Acquired Pneumonia Organization (CAPO) was created in 1999, with the goal of facilitating international research in the field of community-acquired pneumonia (CAP). Led by Dr. Julio Ramirez, Chief of Infectious Diseases at the University of Louisville, CAPO includes investigators from over 30 countries and 130 hospitals; it strives to advance the state-of-the-art in CAP therapy world-wide.

The primary objective of the core study is to evaluate the quality of care delivered to hospitalized patients with CAP. The core study protocol and case report form were developed by the original steering committee and have been through several updates over the years.

In addition to the original study, several secondary analyses have been performed using CAPO data on various topics including, but not limited to:

  • CAP and cardiac complications
  • Vaccine effectiveness and CAP
  • Differences in mortality between various CAP regions
  • The effect of cancer on CAP outcomes
  • Managing elderly patients with CAP

For a selected list of publications produced by CAP investigators, consult our publications page.


From the beginning the CAPO case report form and database have been maintained by members of the CAPO data coordinating center at the University of Louisville Division of Infectious Diseases. Recently those duties have been moved to the Clinical Research Support Program (CRSP) also at the University of Louisville. The director of the CRSP is Dr. Julio Ramirez, with Paula Peyrani, Timothy Wiemken, and William Mattingly as assistant directors. The CRSP is responsible for maintaining the CAPO database, updating the case report forms, performing statistical analysis of the CAPO data for publication, enrolling new CAPO investigators, and engaging the CAPO community with periodic and ad-hoc virtual meetings.

The CRSP also maintains this website to disseminate information about CAPO and the CAPO database. In particular, potential and new investigators will want to consult the resources page which contains the protocol, data collection manual and case report form for CAPO. If you have questions about CAPO, our contact page contains information for contacting us.

Dr. Julio Ramirez
Chief, Infectious Diseases
Director, Clinical Research Support Program
University of Louisville

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